Table 1 Multivariate Cox regression analysis of the risk of recurrence or death related to demographic and pathological variables in CC patients
From: ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer
| Â | Â | Disease-free survival | Overall survival | ||
|---|---|---|---|---|---|
Variable | Â | HR (95% CI) | p value | HR (95% CI) | p value |
Age |  | 1.02 (0.98–1.06) | 0.310 | 1.07 (1.02–1.12) | 0.003 |
Tumor size |  | 0.82 (0.62–1.08) | 0.150 | 0.97 (0.79–1.19) | 0.780 |
Stage | II | 1 | 0.008 | 1 | 0.940 |
III | 36.33 (2.57–513) | 0.005 (0.00–0.01) | |||
LNI | No | 1 | 0.039 | 1 | 0.930 |
Yes | 0.07 (0.006–0.87) | 472 (0.93–563) | |||
Blood vessel invasion | No | 1 | 0.340 | 1 | 0.750 |
Yes | 1.67 (0.58–4.83) | 1.51 (0.51–4.52) | |||
Perineural invasion | No | 1 | 0.370 | 1 | 0.980 |
Yes | 1.56 (0.59–4.14) | 0.99 (0.36–2.73) | |||
ZEB1 hypermethylation | No | 1 | 0.015 | 1 | 0.006 |
Yes | 0.22 (0.06–0.74) | 0.18 (0.05–0.6) | |||