Fig. 1
From: ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer
A Ideograms showing the location of the gene regions analyzed by pyrosequencing (PyroSeq) for CDX2, FRMD6 and ZEB1 genes, obtained from UCSC Genome Browser (Human GRCh37/hg19). The transcription start sites (TSSs), and the location of the PCR and sequencing primers are displayed. CpGs sites are represented by vertical bars. B Average percentage of CpGs methylation values within CDX2 and ZEB1 genes, and CpG methylation value of FRMD6 gene of each non-neoplastic colon (N) and each tumor (T) obtained by PyroSeq. The horizontal line represents the mean of both series (*p < 0.05, *** p < 0.001)