Table 2 CpG sites significantly associated with treatment efficacy in chronic migraine
CpG | Gene | Chr | Location in gene | Effect size [SD] | P value | Direction (T0 to T1) | Analysis Model |
|---|---|---|---|---|---|---|---|
cg14377273 | HDAC4 | 2 | Body | 0.02 [0.016] | 8.9 × 10–8 | reduced DNAm | longitudinal DNAm ~ MHD |
cg15205829 | MARK3 | 14 | Body | 0.02 [0.001] | 4.1 × 10–8 | not applicable | baseline DNAm ~ MMD |