Table 2 Characteristics of the patients included in the validated cohort

PRU

198.50 ± 74.70

274.44 ± 64.94

149.56 ± 46.90

5.185

0.000

InhibitionPer

0.30 ± 0.20

0.20 ± 0.18

0.41 ± 0.16

 − 3.753

0.001

Baseline

280.03 ± 58.64

303.72 ± 46.80

256.33 ± 60.84

2.619

0.013

Age (year)

59.50 ± 9.49

62.00 ± 8.87

57.00 ± 9.67

1.617

0.115

Male, n (%)

27 (75.0)

14 (77.8)

13 (72.2)

–

1.000

Hypertension, n (%)

24 (66.7)

12 (66.7)

12 (66.7)

–

–

Diabetes, n (%)

4 (11.1)

4 (22.2)

0 (0.0)

–

0.104

Hyperlipidaemia, n (%)

19 (52.8)

8 (44.4)

11 (61.1)

–

0.505

Smoking history, n (%)

13 (36.1)

6 (33.3)

7 (38.9)

–

1.000

Drinking history, n (%)

8 (22.2)

3 (16.7)

5 (27.8)

–

0.691

Statin

1.75 ± 0.81

1.61 ± 0.78

1.89 ± 0.83

 − 1.035

0.308

PPI

0.83 ± 0.65

0.94 ± 0.73

0.72 ± 0.57

1.019

0.315

BMI (kg/m²)

23.96 ± 2.96

24.01 ± 2.36

23.90 ± 3.53

0.118

0.907

Stnet

1.25 ± 0.94

1.61 ± 0.85

0.89 ± 0.90

2.475

0.018

LVEF (%)

58.61 ± 8.71

60.16 ± 9.32

57.06 ± 8.01

1.072

0.291

TC (mmol/L)

4.50 ± 1.28

4.62 ± 1.01

4.37 ± 1.52

0.568

0.574

TG (mmol/L)

1,51 ± 0.90

1.45 ± 0.69

1.57 ± 1.09

 − 0.373

0.711

HDL (mmol/L)

1.03 ± 0.30

1.08 ± 0.38

0.98 ± 0.20

1.022

0.314

LDL (mmol/L)

2.64 ± 1.00

2.78 ± 1.06

2.51 ± 0.95

0.799

0.430

GLU (mmol/L)

5.74 ± 1.37

5.49 ± 1.36

6.00 ± 1.36

 − 1.111

0.274

HbA1C (%)

5.99 ± 0.79

5.99 ± 0.93

5.98 ± 0.65

0.021

0.984

ALT (U/L)

39.67 ± 36.23

38.94 ± 31.15

40.39 ± 41.60

 − 0.118

0.907

AST (U/L)

100.42 ± 178.88

111.56 ± 172.84

89.28 ± 189.06

0.369

0.714

TBIL (µmol/L)

15.29 ± 7.13

14.08 ± 8.06

16.50 ± 6.05

 − 1.020

0.315

Albumin (g/L)

39.46 ± 3.36

39.36 ± 3.43

39.56 ± 3.38

 − 0.171

0.865

BUN (mmol/L)

5.17 ± 1.04

5.20 ± 1.23

5.15 ± 0.84

0.148

0.884

CREA (µmol/L)

72.88 ± 17.85

71.91 ± 16.80

73.86 ± 19.29

 − 0.324

0.748

UA (µmmol/L)

343.42 ± 120.03

325.33 ± 145.85

361.50 ± 87.74

 − 0.901

0.374

hsCRP (mg/L)

6.89 ± 10.20

5.49 ± 10.51

8.30 ± 9.98

 − 0.824

0.416

PLT (*109/L)

208.06 ± 80.34

197.17 ± 62.30

218.94 ± 95.69

 − 0.809

0.424