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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Long-term decitabine/retinoic acid maintenance treatment in an elderly sAML patient with high-risk genetics

Fig. 1

A Cytological diagnosis of tAML. Left panel myeloblast in PB smear, middle panel population of blasts (> 50%) in BM (Pappenheim-staining), right panel POX-positive blasts in BM (POX-staining), original magnification × 63. B Best response to DAC + ATRA. Left panel PB smear with mature neutrophil granulocyte, right panel BM with normal trilineage hematopoiesis (Pappenheim-staining), original magnification × 40. C Kinetics of Hgb level (upper graph, red line), RBC transfusion requirements and timepoints of inpatient hospitalization. Bars depicting each DAC cycle (blue d1-5, orange d1-3). Lower graph showing proportion of del(5q) (blue line) detected with FISH, emerging mutations are depicted at the timeline. Timeframe over 5 years from therapy initiation with DAC + ATRA until patient deceased. Hgb Hemoglobin, PB Peripheral blood, POX Peroxidase, RBC Red blood cell

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Clinical Epigenetics

ISSN: 1868-7083

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