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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma

Fig. 2

RSPO3 expression is regulated by DNA methylation in CCA. A Differential DNA methylation of RSPO3 in CCA cell lines. B The expression level of RSPO3 in CCA cell lines. C Expression levels of RSPO3 in CCA cell lines as related to its promoter methylation. D, E Expression of RSPO3 mRNA in CCA cells QBC939 and HCCC9810 after DAC treatment. Data are shown normalized to β-actin. F, G The proliferation of DAC-treated CCA cells QBC939 and HCCC9810 was performed using Cell Counting Kit-8 (CCK-8)

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Clinical Epigenetics

ISSN: 1868-7083

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