Skip to main content
Fig. 2 | Clinical Epigenetics

Fig. 2

From: Abnormal expression of PRKAG2-AS results in dysfunction of cardiomyocytes through regulating PRKAG2 transcription by interacting with PPARG

Fig. 2

A positive correlation between PRKAG2-AS and PRKAG2 in cardiac ischemia. A An analysis of 6 heart samples from healthy donors and 6 heart samples from patients with ischemic cardiomyopathy showed a significant reduction in the expression of PRKAG2-AS in the hearts of those suffering from ischemic cardiomyopathy than in the hearts of healthy individuals. B Expression of PRKAG2b and PRKAG2d was reduced in human ischemic hearts. C A positive correlation between the expression of PRKAG2-AS and PRKAG2b or PRKAG2d was observed in ischemic cardiomyopathy. D-E Flow cytometry analysis demonstrated apoptosis and necrosis of cardiomyocytes induced by hypoxia. Fā€“H The expression of PRKAG2-AS, PRKAG2b, and PRKAG2d was significantly reduced in hypoxic cardiomyocytes

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us