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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Multi-tissue epigenetic analysis identifies distinct associations underlying insulin resistance and Alzheimer’s disease at CPT1A locus

Fig. 1

Manhattan plot of the EWAS of HOMA-IR conducted in the Framingham Heart Study. HOMA-IR Homeostatic model assessment of insulin resistance. The −log10(P)-value for each blood DNA methylation marker (CpG) on the y axis is plotted against the build 37 genomic position on the x axis (chromosomal coordinate). The dashed horizontal red line indicates the genome-wide significance threshold of P = 1.1 × 10−7 and the dashed horizontal blue line indicates the threshold of P = 10−5. Association analysis (N = 3167) was adjusted for age, sex, and body mass index

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Clinical Epigenetics

ISSN: 1868-7083

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