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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

Fig. 4

Combination treatment induces a pro-differentiation phenotype in RD spheroids and cell death in RH30 spheroids. Representative images of haematoxylin and eosin staining (H & E) and immunohistochemistry (IHC) of proteins in RD A and RH30 B spheroids after 6 days of treatment. Percentage of cells stained in immunohistochemistry (IHC) of proteins in RD and RH30 spheroids after 6 days treatment using antibodies targeting C Ki67, D H3K27me3, E Myosin Heavy Chain (MHC), F Myogenin and G Cleaved Caspase 3

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