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Table 2 Overlapping differential methylation in mouse and human KS1 signatures

From: Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model

Mouse gene

Mouse signature sites

Mouse direction

Human gene

Human signature sites

Human direction

Agreement

Ado

1

Hypo

ADO

2

Hypo

Yes

Dlg4

1

Hyper

DLG4

1

Hypo

 

Hlx

1

Hypo

HLX

1

Hypo

Yes

Hnrnpa1

2

Hypo

HNRNPA1

1

Hypo

Yes

Il17re

2

Hypo

IL17RE

1

Hyper

 

Kirrel3

1

Hypo

KIRREL3

1

Hyper

 

Ksr1

1

Hyper

KSR1

1

Hyper

Yes

Rab11fip3

1

Hypo

RAB11FIP3

1

Hypo

Yes

Rai1

1

Hyper

RAI1

1

Hyper

Yes

Rps8

3

Hypo

RPS8

1

Hypo

Yes

Rrp12

1

Hypo

RRP12

2

Hypo

Yes

Sema6b

3

Hypo

SEMA6B

1

Hypo

Yes

Sh3rf3

1

Hypo

SH3RF3

2

Hypo

Yes

Slitrk5

1

Hyper

SLITRK5

3

Hyper

Yes

Slmap

2

Hypo

SLMAP

1

Hypo

Yes

Tnfaip2

1

Hypo

TNFAIP2

3

Hypo

Yes

Vac14

1

Hyper

VAC14

1

Hypo

 

Zbtb46

2

Hypo

ZBTB46

1

Hypo

Yes

Zmiz1

3

Hyper

ZMIZ1

4

Hyper

Yes