Skip to main content
Fig. 5 | Clinical Epigenetics

Fig. 5

From: Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model

Fig. 5

Ar-42 treatment Kmt2d+/βGeo mice rescue a subset of signature CpGs. A Heatmap of signature sites with AR-42 treated samples included, showing that there is no broad methylation effect of treatment (as visualized by dendrogram, with treated samples intermixed with untreated but still clustering by genotype, providing further validation of the signature. B Three CpGs with significant methylation changes in AR-42 treated animals. Asterisks represent significant differential methylation (FDR p-value < 0.05) as tested by limma regression

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us