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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model

Fig. 4

Linear relationship between brain volume and DNAm level at 27 CpGs in Kmt2d+/βGe mice (left), as compared to WT mice (right). Y-axis represents PC1 scores of each animal, derived from PCA of 27 signature CpGs significantly associated with total brain volume. Blue lines represent line of best fit and statistics were generated from a linear regression performed within each group

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