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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Peripheral blood DNA methylation and neuroanatomical responses to HDACi treatment that rescues neurological deficits in a Kabuki syndrome mouse model

Fig. 1

Size and brain volume deficits in Kmt2d+/βGeo mice. A Body weights (g) of vehicle-treated animals at sacrifice. Kmt2d+/βGeo animals were significantly smaller than WT (t-test p-value < 0.05). B Absolute (left) and relative (right) volume changes in Kmt2d+/βGeo for all structures with q-value < 0.05. As observed in left column, volume loss is consistent across brain structures. C Total brain volume (mm3) vehicle-treated animals. Kmt2d+/βGeo volumes were significantly smaller than WT (t-test p-value < 0.05)

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Clinical Epigenetics

ISSN: 1868-7083

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