Fig. 6

Coefficient plots for multivariable analysis of mutations (A) and chromosomal aberrations (B). A Coefficient plot for contained mutations, age and gender in comparison to the 12-CpG-signature. B Coefficient plot for karyotypes, age and gender in comparison to the 12-CpG-signature. Plots include the 95%-confidence interval for each predictor. Values in respective tables are the results from multiple logistic regression modelling. A model containing both mutational and cytogenetic variables could not be fitted because the sample size was too small to estimate all model parameters with sufficient confidence. Due to very small samples sizes for the del(5q)/-5 and t(11q23) groups (n = 2 each), both groups were combined with the group „other “ (n = 11) for the multivariable analysis. Karyotype merged comprises “del(5q)/-5 “, “t(11q23)“, “other “