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Fig. 6 | Clinical Epigenetics

Fig. 6

From: KDM4C-mediated senescence defense is a targetable vulnerability in gastric cancer harboring TP53 mutations

Fig. 6

QC6352 possessed strong anti-cancer activity. A Bar plot representing the IC50 of genotoxic agents and QC6352 in the indicated cell lines. B-D NCI-N87, HGC27, and AGS cells were treated with QC6352 (96 nM for NCI-N87, 79 nM for HGC27 and 44 nM for AGS) and then subjected to cell proliferation assays (B), colony formation assays (C) and Transwell migration assays (D). ***P < 0.001. P values were determined by a two-tailed unpaired t test. Data were presented as mean ± SEM of three independent experiments

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