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Table 1 Associations of mAge measures with smoking group

From: Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers

 

Mean (SD)

Tukey HSD testing, P

All participants (n = 69)

NS (n = 39)

EC (n = 14)

SM (n = 16)

EC versus NS

SM versus NS

SM versus EC

Chronological age

26 (2.8)

25.6 (3.0)

26.8 (2.7)

26.2 (2.7)

0.40

0.77

0.85

mAge

       

Grim-mAge

39.56 (3.82)

37.85 (3.36)

41.47 (2.61)

42.07 (3.73)

0.002

0.0002

0.88

TL-mAge

6.06 (0.14)

6.11 (0.14)

6.01 (0.12)

5.99 (0.12)

0.02

0.006

0.94

Horvath-mAge

24.95 (4.23)

24.01 (4.10)

25.72 (5.13)

26.59 (3.14)

0.38

0.10

0.84

Age-Accel

       

Grim-mAA

2.90E−11 (2.64)

− 1.35 (2.08)

1.15 (1.98)

2.29 (2.35)

0.001

 < 0.0001

0.31

TL-mAA

− 1.61E−18 (0.14)

0.05 (0.13)

− 0.05 (0.13)

− 0.07 (0.11)

0.05

0.008

0.88

Horvath-mAA

1.45E−11 (3.72)

− 0.68 (3.21)

0.22 (4.52)

1.48 (3.89)

0.71

0.12

0.62

  1. NS never-smokers, EC e-cig users, SM smokers
  2. Tukey HSD adjusted P < 0.05 in bold
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Clinical Epigenetics

ISSN: 1868-7083

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