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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Accelerated epigenetic age, inflammation, and gene expression in lung: comparisons of smokers and vapers with non-smokers

Fig. 4

Differentially expressed Grim-mAA-associated genes in TCGA and COPD datasets. A Stacked bar charts display the percentage of altered samples with higher (orange) or lower (gray) expression in tumors compared to adjacent normal tissues (y-axis) for adenocarcinoma and squamous cell carcinoma by the gene (x-axis). Asterisks represent overlapping genes between adenocarcinoma and squamous cell carcinoma datasets. B Dot plots comparing the log2 expression (y-axis) between COPD cases (red) and controls (gray). Each open circle represents individual COPD cases and controls. Each line represents the mean log2 expression for each group. C Venn diagram of overlapping significant genes from TCGA, COPD data sets, and Grim-mAA-associated genes

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Clinical Epigenetics

ISSN: 1868-7083

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