Table 2 20 biomarkers selected for the validation phase
MethylationEPIC probe ID | Gene symbol | Pyrosequenced region (GRCh37/hg19) | CpG sites analyzed | Relation to CpG island | Regulatory feature | |
|---|---|---|---|---|---|---|
CG2 | cg05445162 | GCKR | chr2:27,730,152–27730225 | 1 | Opensea | Body |
CG3 | cg11113216 | GALNT9 | chr12:132,847,616–132,847,751 | 3 | Island | Body |
CG4 | cg06522913 | IDH2 | chr15:90,630,673–90630817 | 1 | Opensea | Body |
CG5 | cg14838992 | WARS | chr14:100,814,702–100814791 | 3 | Opensea | Body |
CG6 | cg06148974 | chr4:1,864,164–1,864,242 | 3 | Island | ||
CG8 | cg03111938 | chr6:169,289,158–169,289,293 | 5 | Island-shelf | ||
CG9 | cg07253636 | NOSIP | chr19:50,077,734–50077874 | 2 | Opensea | 5'UTR |
CG11 | cg25942688 | CENPA | chr2:27,016,702–27016821 | 1 | Opensea | 3'UTR |
CG12 | cg01987330 | chr3:142,797,286–142,797,375 | 1 | Opensea | ||
CG14 | cg10641001 | RDX | chr11:110,104,045–110104122 | 2 | Opensea | Body |
CG15 | cg01550272 | UPF3A | chr13:115,050,863–115050975 | 1 | Island-shelf | Body |
CG16 | cg03640756 | PCDHG gene cluster | chr5:140,864,546–140864667 | 11 | Island | Body |
CG17 | cg26024530 | chr10:130,281,707–130281864 | 3 | Opensea | ||
CG19 | cg15442105 | ZNF498 | chr7:99,227,410–99227486 | 4 | Opensea | Body |
CG20 | cg04544475 | RNF43 | chr17:56,435,427–56,435,508 | 3 | Opensea | Body |
CG21† | cg16639692 | lncRNA LOC648987 | chr5:43,037,639–43037813 | 1 | Island-shore | |
CG23† | cg04600077 | lncRNA ENSG00000249966 | chr5:1,852,792–1,852,864 | 1 | Island-shore | |
CG24‡ | cg14503564 | LDB2 | chr4:16,723,341–16,723,457 | 6 | Opensea | Body |
CG25§ | cg18044585 | EIF2C2 | chr8:141,619,395–141,619,528 | 6 | Opensea | Body |
CG26‡ | cg23653187 | PNPLA3 | chr22:44,319,222–44,319,299 | 2 | Island-shore | TSS1500 |