Fig. 4
Screening of m6A regulators associated with VGF. A Forest map illustrates the survival analysis of m6A methylases and demethylases in LUAD. B The scale-free topology fitting index R2 reaches 0.9. C A hierarchical clustering tree is shown in LUAD. D Interaction relationship analysis of co-expressed genes. E The network heatmap visualized the interactions between the 24 modules. F Correlation between the gene module and m6A-related genes in LUAD. G The light-yellow module was significantly positively correlated with the module genes. H Volcano plot of differential gene expression in METTL3-knockdown A549 cells compared to control cells. I Venn diagrams were used to screen the VGF gene. J Integrative Genomics Viewer (IGV) tracks displaying MeRIP-seq read distributions in VGF. K mRNA density coverage