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Fig. 4 | Clinical Epigenetics

Fig. 4

From: A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism

Fig. 4

Specific genes methylation changes related to eye development and retinoid metabolism are mainly. A The Venn diagram shows 32 differentially methylated genes related to eye development with 16 hyper and 16 hypomethylated genes. At the same manner, the Venn diagram 3 differentially methylated genes related to retinoid metabolism with 1 hyper- and 2 hypomethylated genes. B Top 10 most significantly enriched JENSEN Disease terms for differentially methylated genes involved in eye development and retinoid metabolism (FDR < 0.05)

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