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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis

Fig. 5

Multivariable Cox-regression model for all-cause and cardiac mortality after TAVI. The final multivariable Cox-regression models for all-cause (A) and cardiac (B) mortality. A The final model included AF and DM as independent predictors of all-cause mortality, whereas an increase in IRX3 promoter methylation level was protective. B The final model included AF and DM as independent predictors of cardiac mortality, whereas LVEF was protective. IRX3 promoter methylation level showed no influence on cardiac mortality. CI: confidence interval; HR: hazard ratio; LVEF: left ventricular ejection fraction. * p < 0.05, ** p < 0.01

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Clinical Epigenetics

ISSN: 1868-7083

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