Fig. 3

Significant inverse correlation between circulating IRX3 promoter methylation level and cardiac fibrosis. The circulating IRX3 promoter methylation and the amount of cardiac fibrosis correlate inversely on a significant level but with a relatively weak correlation coefficient (r = 0.215). Each dot representing one individual (n = 100), regression shown as simple linear regression. Pearson’s correlation coefficient (Pearson’s r) and p value were calculated