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Table 6 Diagnostic value for colorectal cancer of cumulative methylation levels

From: Association of DNA methylation of vitamin D metabolic pathway related genes with colorectal cancer risk

Gene

Model 1

 

Model 2

 

all CpG sites

 

significant CpG sites

 

AUC

95% CI

P

 

AUC

95% CI

P

VDR

0.56

0.48–0.64

0.15

 

0.65

0.57–0.72

0.001

CYP24A1

0.51

0.43–0.59

0.75

 

0.63

0.56–0.71

< 0.001

CYP27B1

0.52

0.44–0.60

0.56

 

–

–

–

CYP2R1

0.53

0.45–0.61

0.45

 

–

–

–

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Clinical Epigenetics

ISSN: 1868-7083

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