Table 3 Gene ontology enrichment. Top 10 significant biological process (BP) pathways for each sleep measure
Sleep Measure | GO | Term | Ontology1 | N2 | Mapped3 | q-value |
|---|---|---|---|---|---|---|
Bedtime (hh:mm) | ||||||
PSG | GO:0032502 | Developmental process | BP | 6469 | 471 | 2.52E-11 |
GO:0048468 | Cell development | BP | 2034 | 192 | 3.17E-11 | |
GO:0048856 | Anatomical structure development | BP | 5948 | 437 | 5.27E-11 | |
GO:0007275 | Multicellular organism development | BP | 5454 | 402 | 7.37E-10 | |
GO:0007399 | Nervous system development | BP | 2358 | 207 | 1.40E-09 | |
GO:0048731 | System development | BP | 4887 | 366 | 1.43E-09 | |
GO:0030182 | Neuron differentiation | BP | 1357 | 135 | 5.01E-09 | |
GO:0030154 | Cell differentiation | BP | 4234 | 323 | 5.19E-09 | |
GO:0009653 | Anatomical structure morphogenesis | BP | 2694 | 225 | 7.61E-09 | |
GO:0048699 | Generation of neurons | BP | 1501 | 144 | 8.65E-09 | |
Sleep latency (min) | ||||||
Self-report | GO:0006357 | Regulation of transcription by RNA polymerase II | BP | 2539 | 86 | 7.0E-03 |
GO:0000122 | Negative regulation of transcription by RNA polymerase II | BP | 873 | 40 | 7.0E-03 | |
GO:0009653 | Anatomical structure morphogenesis | BP | 2694 | 89 | 7.0E-03 | |
GO:0048598 | Embryonic morphogenesis | BP | 569 | 30 | 7.0E-03 | |
GO:0007399 | Nervous system development | BP | 2358 | 80 | 7.4E-03 | |
GO:0022008 | Neurogenesis | BP | 1613 | 60 | 8.4E-03 | |
GO:0019219 | Regulation of nucleobase-containing compound metabolic process | BP | 4006 | 119 | 9.9E-03 | |
GO:0009790 | Embryo development | BP | 992 | 42 | 9.9E-03 | |
GO:0032502 | Developmental process | BP | 6469 | 174 | 9.9E-03 | |
GO:0006366 | Transcription by RNA polymerase II | BP | 2695 | 87 | 9.9E-03 | |
ACT | GO:0050794 | Regulation of cellular process | BP | 11,346 | 374 | 1.3E-04 |
GO:0007399 | Nervous system development | BP | 2358 | 108 | 2.1E-04 | |
GO:0030154 | Cell differentiation | BP | 4234 | 169 | 2.1E-04 | |
GO:0048869 | Cellular developmental process | BP | 4315 | 171 | 2.1E-04 | |
GO:0007275 | Multicellular organism development | BP | 5454 | 202 | 8.9E-04 | |
GO:0032502 | Developmental process | BP | 6469 | 230 | 1.7E-03 | |
GO:0048856 | Anatomical structure development | BP | 5948 | 214 | 1.8E-03 | |
GO:0022008 | Neurogenesis | BP | 1613 | 77 | 1.8E-03 | |
GO:0050789 | Regulation of biological process | BP | 12,294 | 388 | 1.9E-03 | |
GO:0065007 | Biological regulation | BP | 13,019 | 406 | 2.1E-03 | |
PSG | GO:0048856 | Anatomical structure development | BP | 5948 | 165 | 2.5E-03 |
GO:0044260 | Cellular macromolecule metabolic process | BP | 8227 | 212 | 2.5E-03 | |
GO:0050793 | Regulation of developmental process | BP | 2514 | 84 | 4.6E-03 | |
GO:0006366 | Transcription by RNA polymerase II | BP | 2695 | 87 | 6.5E-03 | |
GO:0006357 | Regulation of transcription by RNA polymerase II | BP | 2539 | 83 | 6.5E-03 | |
GO:0009058 | Biosynthetic process | BP | 6216 | 165 | 7.0E-03 | |
GO:0009888 | Tissue development | BP | 2016 | 69 | 7.0E-03 | |
GO:1,901,576 | Organic substance biosynthetic process | BP | 6134 | 163 | 7.0E-03 | |
GO:0032502 | Developmental process | BP | 6469 | 170 | 7.0E-03 | |
GO:0007275 | Multicellular organism development | BP | 5454 | 148 | 7.5E-03 | |