Evaluation of pediatric epigenetic clocks across multiple tissues

Clinical Epigenetics

Table 1 Demographic information for ECHO participants included in this study

	Cord blood (N = 1938)	CBMC (N = 142)	Blood spot (N = 701)	Placenta (N = 579)	Buccal (N = 552)	PBMC (N = 290)	Peripheral whole blood (N = 353)	Total (N = 4555)
Self-reported race
American Indian or Alaska Native	11	< 5*	6	< 5*	< 5*	< 5*	< 5*	24
Asian	31	< 5*	21	18	19	< 5*	< 5*	94
Black	364	112	124	122	99	117	50	988
Hawaiian or other Pacific Islander	< 5*	< 5*	< 5*	< 5*	7	< 5*	< 5*	9
Multiple race	176	9	65	38	104	11	153	556
Other race	94	< 5*	12	16	36	< 5*	< 5*	163
White	929	< 5*	435	367	284	142	143	2302
Missing	333	17	36	14	< 5*	16	< 5*	419
Sex
Male	914	70	366	313	303	144	163	2273
Female	1,024	72	335	266	249	146	190	2282
Birth term
Preterm	< 5*	< 5*	272	399	480	< 5*	< 5*	1151
Term	1,938	142	439	180	72	290	353	3414
Array type
27K	159	< 5*	< 5*	< 5*	< 5*	< 5*	< 5*	159
450K	1,194	< 51	253	59	< 51	150	307	1963
EPIC	585	142	448	520	552	140	46	2433
Gestational age at delivery	39.1 ± 1.5	39.0 ± 1.4	33.7 ± 8.6	29.8 ± 6.2	28.1 ± 4.3	39.1 ± 1.2	39.0 ± 1.7
Age at sample collection	0	0	0	0	74.3 ± 40.3 days	9.1 ± 3.0 years	6.0 ± 2.8 years

*It is an ECHO requirement that table cells and figures that report data from fewer than 5 participants must be suppressed to protect Participant confidentiality (i.e., marked as < 5)
CBMC Cord blood mononuclear cells, PBMC Peripheral blood mononuclear cells

ISSN: 1868-7083