Table 1 Maternal and child characteristics, by detection of acetaminophen
Variable | Detection of acetaminophen in cord plasma (n = 570) | P-value | |
|---|---|---|---|
No. not detected | No. detected | ||
Number of participants | 474 (83.2%) | 96 (16.8%) | |
Male | 261 (55.1%) | 54 (56.2%) | 0.92 |
Maternal race/ethnicity | 0.03 | ||
Non-Hispanic white | 27 (5.7%) | 9 (9.4%) | |
Non-Hispanic black | 322 (67.9%) | 52 (54.2%) | |
Hispanic | 125 (26.4%) | 35 (36.5%) | |
Gestational age at birth in weeks, mean (SD) | 38.79 (2.20) | 37.75 (3.18) | < 0.001 |
Preterm birth (gestational age < 37 weeks) | 69 (14.6%) | 31 (32.3%) | < 0.001 |
Birth weight in kilograms, mean (SD) | 3.14 (0.64) | 2.96 (0.78) | 0.02 |
Low birth weight (birth weight < 2500 g) | 81 (17.1%) | 19 (19.8%) | 0.63 |
Parity: primiparous | 199 (42.0%) | 53 (55.2%) | 0.02 |
Cesarean section | 147 (31.0%) | 36 (37.5%) | 0.26 |
Intrauterine inflammation | 44 (9.3%) | 26 (27.1%) | < 0.001 |
Maternal education | 0.90 | ||
High school or less | 312 (65.8%) | 65 (67.7%) | |
Some college | 105 (22.2%) | 21 (21.9%) | |
College degree or above | 57 (12.0%) | 10 (10.4%) | |
Maternal marital status: not married | 310 (65.4%) | 69 (71.9%) | 0.27 |
Maternal age in years at delivery, mean (SD) | 28.34 (6.56) | 27.65 (6.61) | 0.35 |
Any maternal smoking during pregnancy | 91 (19.2%) | 20 (20.8%) | 0.82 |
Any maternal alcohol use during pregnancy | 34 (7.2%) | 12 (12.5%) | 0.12 |
Maternal diabetes mellitus | 0.03 | ||
Chronic diabetes | 19 (4.0%) | 10 (10.4%) | |
Gestational diabetes | 33 (7.0%) | 6 (6.2%) | |
No diabetes | 422 (89.0%) | 80 (83.3%) | |
Maternal preeclampsia or HELLP syndrome | 29 (6.1%) | 22 (22.9%) | < 0.001 |
Maternal pre-pregnancy BMI, mean (SD) | 26.65 (6.25) | 26.57 (6.11) | 0.91 |
Maternal stress level during pregnancy | 0.60 | ||
Not stressful | 186 (39.2%) | 33 (34.4%) | |
Average | 205 (43.2%) | 43 (44.8%) | |
Very stressful | 83 (17.5%) | 20 (20.8%) | |