Fig. 3

The association of cytokines/chemokines and immune checkpoint molecular in serum with clinical parameters. A and B The significant difference in serum level of PDCD1 and ICAM1 between LGI1 encephalitis patients with favorable and those with poor prognosis in one-year follow-up. C There were significant relationship between CCL15 and OCB occurrence in patients with LGI1 encephalitis. D The significant difference of serum PD-L2, CCL24 and IFNγ observed in LGI1 encephalitis patients with/without blood–CSF barrier dysfunction. E There was significant relationship between serum TNFRSF1A and hyponatremia in patients with LGI1 encephalitis. F The difference of serum PD-L2, TNFɑ, and CCL2 in LGI1 encephalitis patients with/without MRI abnormality. G–J The correlations between serum TIMP2, PD-L2, CD86, CCL24 and CSF protein level in the patients with LGI1 encephalitis. K–M ROC of PDCD1, ICAM1 and their combination for poor outcomes in one-year follow-up in LGI1 encephalitis patients. CSF cerebrospinal fluid. *p < 0.05