Table 1 Number of age-related differentially methylated CpGs (aDMCs) in the discovery and replication stage
From: The inactive X chromosome accumulates widespread epigenetic variability with age
| Â | Males | Females | ||||
|---|---|---|---|---|---|---|
N | aDMCs (loss/gain) | Replication rate | N | aDMCs (loss/gain) | Replication rate | |
Discovery | ||||||
BIOS Blood | 1688 | 1837 (718/1119) | – | 2343 | 80 (41/39) | – |
Replication | ||||||
Johansson Blood | 341 | 1371 (532/839) | 75% | 388 | 79 (41/38) | 99% |
Reynolds Monocytes | 583 | 340 (195/145) | 25% | 603 | 34 (24/10) | 43% |
Doubly replicated | – | 316 (175/141) | 17% | – | 33 (24/9) | 41% |