Fig. 5
From: The inactive X chromosome accumulates widespread epigenetic variability with age
Annotation of aDMCs and aVMCs in males and females. a Categories of mean methylation level of aDMCs and aVMCs in males and females (intermediate methylated: 0.25 < β < 0.7, hypomethylated: β < 0.25, hypermethylated: β > 0.7). b Fraction of aDMCs and aVMCs in CGI-related features (CGI, CGI shore, and non-CGI). c XCI status annotation of aDMCs and aVMCs in females. Annotation was based on colocalization (< 2kb) to TSS categorized as Subject to XCI, Escape XCI and Variably escape XCI. aDMCs—age-related differentially methylated CpGs, aVMCs—age-related variably methylated CpGs, CGI—CpG island, XCI—X-chromosome inactivation