Table 1 Summary statistics and comparison of age-related parameters collected for blood samples N = 10 with a mean age = 44.0 ± 26.1 (age range 7–78)
Epigenetic clock | Statistics | EPIC | Ion AmpliSeq | SureSelect | |||
|---|---|---|---|---|---|---|---|
Original | Transformed | Original | Transformed | Original | Transformed | ||
VISAGE blood age | Mean predicted value ± SD | 40.3 ± 26.1* | NA | 46.9 ± 29.6** | 41.8 ± 27.4 | 42.6 ± 29.6** | NA |
Mean difference between replicates | 2.9 ± 2.0 | NA | 1.2 ± 0.4 | 1.2 ± 0.4 | 2.5 ± 1.6 | 2.3 ± 1.5 | |
Mean absolute error of prediction (MAE) | 3.9 ± 2.9 | NA | 4.6 ± 2.6 | 2.7 ± 2.5 | 3.9 ± 2.7 | NA | |
Hannum age | Mean predicted value ± SD | 42.7 ± 21.2 | 41.7 ± 23.3 | 49.0 ± 25.4 | 44.5 ± 22.7 | 47.5 ± 22.7 | 43.1 ± 20.3 |
Mean difference between replicates | 1.5 ± 0.9 | 1.6 ± 1.0 | 1.3 ± 1.0 | 1.2 ± 0.9 | 1.1 ± 0.6 | 1.0 ± 0.5 | |
Mean absolute error of prediction (MAE) | 4.3 ± 2.8 | 2.9 ± 2.8 | 5.0 ± 2.7 | 3.6 ± 2.0 | 4.7 ± 1.9 | 4.8 ± 3.5 | |
PoAm | Mean predicted value ± SD | 1.02 ± 0.09 | NA | 1.11 ± 0.08 | 1.04 ± 0.06 | 1.11 ± 0.09 | 1.03 ± 0.06 |
Mean difference between replicates | 0.05 ± 0.04 | NA | 0.05 ± 0.04 | 0.03 ± 0.03 | 0.04 ± 0.02 | 0.03 ± 0.01 | |
Mean absolute error of prediction (MAE) | NA | NA | NA | NA | NA | NA | |
Zhang MRS | Mean predicted value ± SD | − 2.63 ± 0.42 | NA | − 1.52 ± 0.60 | − 2.64 ± 0.36 | − 1.12 ± 0.52 | − 2.40 ± 0.32 |
Mean difference between replicates | 0.11 ± 0.09 | NA | 0.15 ± 0.12 | 0.09 ± 0.07 | 0.08 ± 0.08 | 0.05 ± 0.05 | |
Mean absolute error of prediction (MAE) | NA | NA | NA | NA | NA | NA | |