Fig. 8From: Introduction of a multiplex amplicon sequencing assay to quantify DNA methylation in target cytosine markers underlying four selected epigenetic clocksData transformation by regressing prediction outputs on chronological age and its impact on age prediction accuracy using a Hannum clock applied on different types of data generated for five blood samples analyzed in duplicate. The reference line indicates the line of identity (y = x), i.e. the expected correlation of prediction results with chronological age. Data were transformed using following equations: HannumAge HTS Transformed = 0.64 + (HannumAge HTS*0.89); HannumAge EPIC Transformed = − 5.16 + (HannumAge EPIC*1.10)Back to article page