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Fig. 8 | Clinical Epigenetics

Fig. 8

From: Introduction of a multiplex amplicon sequencing assay to quantify DNA methylation in target cytosine markers underlying four selected epigenetic clocks

Fig. 8

Data transformation by regressing prediction outputs on chronological age and its impact on age prediction accuracy using a Hannum clock applied on different types of data generated for five blood samples analyzed in duplicate. The reference line indicates the line of identity (y = x), i.e. the expected correlation of prediction results with chronological age. Data were transformed using following equations: HannumAge HTS Transformed = 0.64 + (HannumAge HTS*0.89); HannumAge EPIC Transformed = − 5.16 + (HannumAge EPIC*1.10)

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