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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000

Fig. 4

MGISEQ-2000 showed comparable cancer signal detecting ability with NovaSeq6000 at the tumor fraction of 0.1%. A The limit of detection of iLib-NovaSeq, mLib-NovaSeq, and mLib-MGISEQ. The y-axis represented the percentage of observed positive markers. Colors represented data types. There were four replicates at each tumor fraction. Statistical analysis was performed by a two-sided t-test. B The Venn plot showing the most of detected markers was detected in the three types of data. The markers, which were detected in two replicates at the tumor fraction of 0.1, were defined as detected markers

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