Fig. 3
From: Cross-platform comparisons for targeted bisulfite sequencing of MGISEQ-2000 and NovaSeq6000
MGISEQ-2000 showed consistent methylation levels with NovaSeq6000. A, B High correlation of AMFs between iLib-NovaSeq and mLib-MGISEQ (left of A), mLib-NovaSeq and mLib-MGISEQ (right of A), and iLib-NovaSeq and mLib-NovaSeq (B). Color represented the density of points. Points represented the outliers. The black line represented y = x. C PCA of AMFs of the synthetic cfDNA samples. Colors represented the dilution ratios, and shapes represented the data types. D High correlation of CpG methylation levels between iLib-NovaSeq and mLib-MGISEQ. E The variation of CpG methylation levels between mLib-MGISEQ and iLib-NovaSeq datasets around GC contents. The GC content of a CpG site was calculated in a 200-bp window which were extended upstream 100 bp and downstream 100 bp of the CpG