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Fig. 3 | Clinical Epigenetics

Fig. 3

From: DNA methylation as a triage marker for colposcopy referral in HPV-based cervical cancer screening: a systematic review and meta-analysis

Fig. 3

SROC graphs for CIN 2 + (AD) and CIN3+ detection (EH). A and E all the markers reported in all studies; B and F the best markers reported in each study (avoiding considering the same sample more than once); CG the most studied genes (CADM1, FAM19A4, MAL, and miR124-2); and D-H studies which set the threshold to achieve 70% specificity. Gray dots represent referral population-based studies, blue dots represent cohort studies, red dots represent case–control studies, and green dots represent convenience studies

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