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Table 1 Clinicopathological characteristics of patients

From: Circulating NPTX2 methylation as a non-invasive biomarker for prognosis and monitoring of metastatic pancreatic cancer

Patient characteristics

Number of patients (n = 44)

Percentage

Age

 ≤ 66 years

24

54.5

 > 66 years

20

45.5

Sex

 Male

27

61.4

 Female

17

38.6

Stage

 IV

44

100

ECOG

 0

12

27.2

 1

23

52.3

 2

8

18.2

 3

1

2.3

Primary tumor location

 Body

19

43.2

 Tail

12

27.3

 Head

13

29.5

First-line treatment

 Gemcitabine/ ± nab-paclitaxel

37

84.1

 FOLFIRINOX

4

9.1

 No treatment

3

6.8

Number of metastatic lesions

 One

24

54.6

 More than one

20

45.4

Metastatic lesions location

 Hepatic

36

81.8

 Non-hepatic

8

18.2

Tissue Biopsy RAS statusa

 RAS mutated

20

69

 RAS wild-type

9

31

Liquid Biopsy RAS status

 RAS mutated

35

79.5

 RAS wild-type

9

20.5

  1. aFor the analysis of RAS mutational status, primary tumor tissue was available in 65.9% (29/44) of patients