Fig. 2

Age-stratified association between ABCG1 methylation and CHD in the prospective nested case–control study. The point plots showed the methylation differences of CpG sites in the ABCG1 amplicon. The squares indicated the hypomethylation in cases vs. controls, and the triangles indicated the hypermethylation in cases vs. controls. The p values were calculated by logistic regression adjusted for age, gender, smoking, alcohol consumption, hypertension, diabetes, TC, TG, HDL-C, LDL-C, and batch effect. The solid lines indicated the threshold of p value = 0.05