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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time

Fig. 6

Differentially methylated CpG sites between former PICU patients who received glucocorticoids during their stay in the PICU versus those who did not. The boxplots show a univariate presentation of the methylation status (β-value) of the CpG sites for which, adjusting for baseline risk factors and technical variation, a significant difference was found between methylation status in former PICU patients who received glucocorticoid treatment in the PICU (orange) vs those who did not (green). The central lines of the boxplots depict the medians, the boxes the interquartile ranges, and the whiskers are drawn to the furthest point within 1.5 times the interquartile range from the box. PICU: paediatric intensive care unit

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