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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time

Fig. 5

Interaction with sex or age of abnormal DNA methylation in former PICU patients vs healthy children. The boxplots show a univariate presentation of the methylation status (β-value) of the CpG sites for which, adjusting for baseline risk factors and technical variation, a significant interaction was found between differential methylation in former PICU patients (red) vs matched healthy children (blue) and sex (panel A) or “age at exposure” (panel B). The central lines of the boxplots depict the medians, the boxes the interquartile ranges, and the whiskers are drawn to the furthest point within 1.5 times the interquartile range from the box. PICU: paediatric intensive care unit

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