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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Stability selection enhances feature selection and enables accurate prediction of gestational age using only five DNA methylation sites

Fig. 2

Selection probability of CpGs in our analyses that were selected for being predictive in three previously published GA clocks. a The CpGs that were selected in the Haftorn clock (n = 176), b the CpGs that were selected in the Bohlin clock (n = 86), and panel c shows the CpGs that were selected in the Knight clock (n = 140). In each panel, the x-axis displays the beta coefficient for each CpG from the prediction model multiplied by the variance of DNAm in our samples, while the y-axis represents the selection probability calculated from the stability selection analysis. The solid horizontal line denotes a selection probability of 0.5 (i.e., a given CpG has an equal probability of being selected or excluded). The dashed black line denotes the selection probability threshold of 0.73. Orange signifies a selection probability above the threshold of 0.73, and blue signifies a clock-CpG with a selection probability below that threshold

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Clinical Epigenetics

ISSN: 1868-7083

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