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Fig. 3 | Clinical Epigenetics

Fig. 3

From: CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma

Fig. 3

Association of CTLA4 DNA methylation with ICB therapy response and patients’ survival in HNSCC. a Association of CTLA4 DNA methylation with therapy response in a cohort of N = 29 ICB-treated HNSCC patients. Therapy response was grouped in progressive disease (PD), stable disease (SD), and partial response (PR). b Kaplan–Meier analysis of progression-free survival in HNSCC patients stratified according to CTLA4 methylation in pre-ICB-treatment samples. c Kaplan–Meier analysis of overall survival in HNSCC patients stratified according to CTLA4 methylation in pre-ICB-treatment samples. Patient samples were dichotomized based on an optimized cut-off

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Clinical Epigenetics

ISSN: 1868-7083

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