Table 5 mQTLs related to the three CpG sites replicated in EPIPREG

cg12080079

PAX7

rs10907325

PAX7

chr1:18964021

A

T

Systolic blood pressure (PMID: 19609347)

NA

2.02E−05

Body mass index within family tests max measurement (PMID: 21701565)

NA

2.50E−04

Amyotrophic lateral sclerosis (PMID: 28931804)

−0.0112

7.33E−04

Non-insulin-dependent diabetes mellitus (PMID: UKBB)

0.0002683

6.98E−03

rs115326690

chr1:19036153

C

G

Systolic blood pressure (PMID: UKBB)

−0.02669

6.33E−04

Hypertension (PMID: UKBB)

−0.01019

2.57E−03

Psoriasis (PMID: UKBB)

−0.0007364

2.76E−03

rs12563020

chr1:19022599

A

G

Type II diabetes adjusted for BMI (PMID: 28566273)

0.099

4.60E−03

Type II diabetes (PMID: 28566273)

0.064

2.70E−02

rs585075

chr1:19021373

T

C

Gestational diabetes only (PMID: UKBB)

−0.01402

2.56E−02

rs7527312

chr1:19014865

C

G

Body mass index adjusted for smoking in males (PMID: 28443625)

0.0221

3.18E−03

cg04095097

rs10906900

FAM171A1

chr10:15472860

A

G

High-grade serous ovarian cancer (PMID: 28346442)

−0.05032

2.84E−03

rs111256448

ITGA8

chr10:15765261

C

T

Crohn’s disease (PMID: 26192919)

−0.1337

1.27E−03

Diastolic blood pressure (PMID: UKBB)

−0.01169

5.94E−03

rs111920126

ITGA8

chr10:15510921

A

G

Clear cell ovarian cancer (PMID: 28346442)

−0.492

9.00E−04

rs11259597

FAM171A1

chr10:15332911

A

G

Crohn’s disease (PMID: 26192919)

−0.211

3.73E−03

Spondylosis (PMID: UKBB)

0.001257

4.26E−03

rs11259690

ITGA8

chr10:15521768

A

G

Heart attack (PMID: UKBB)

−0.002578

1.36E−03

Type 2 diabetes (PMID: UKBB)

−0.000909

3.31E−02

rs114410649

ITGA8

chr10:15555993

A

G

Non-insulin-dependent diabetes mellitus (PMID: UKBB)

0.0006851

3.28E−02

rs117164512

FAM171A1

chr10:15298845

C

T

Alcoholic hepatitis (PMID: UKBB)

−0.004734

3.62E−03

rs12266863

ITGA8

chr10:15526023

A

G

Rheumatoid arthritis (PMID: 24390342)

−0.08338

8.20E−03

rs12355715

ITGA8

chr10:15534600

C

T

Polyarthrosis (PMID: UKBB)

−0.000452

3.96E−03

rs137882390

FAM171A1

chr10:15265022

A

G

Multiple valve disease (PMID: UKBB)

0.0006208

1.12E−03

Illnesses of father: diabetes (PMID: UKBB)

−0.008409

6.48E−03

rs187688289

FAM171A1

chr10:15471793

C

T

Low grade serous ovarian cancer (PMID: 28346442)

−0.6751

7.10E−04

rs61514659

FAM171A1

chr10:15467588

C

T

Type 2 diabetes (PMID: UKBB)

−0.002412

6.07E−04

rs7087034

ITGA8

chr10:15738818

C

T

–

rs71493225

ITGA8

chr10:15536804

C

T

Ischemic cardiomyopathy (PMID: UKBB)

0.002818

3.17E−04

Insulin-dependent diabetes mellitus (PMID: UKBB)

0.000251

2.98E−02

rs77070234

RP11-455B2.9

chr10:15226599

A

C

Eye problems or disorders: diabetes related eye disease (PMID: UKBB)

0.003402

8.50E−03

rs7915524

FAM171A1

chr10:15293903

C

T

Self-reported mitral regurgitation or incompetence (PMID: UKBB)

0.0001378

2.50E−03

Insulin-dependent diabetes mellitus (PMID: UKBB)

−0.000197

4.12E−02

cg27603605

Non-SNPs