Epigenetic marks associated with gestational diabetes mellitus across two time points during pregnancy

Clinical Epigenetics

Table 2 Top 20 differentially methylated sites (DMPs) between pregnant women with GDM and non-GDM along the pregnancy

ID_CpG	LogFC	P value	FDR	Chr	Gene	Feature	Cgi
cg01459453	0.181	1.06E−11	7.87E−06	1	SELP	Body	Opensea
cg12432693	−0.057	4.07E−11	1.51E−05	11	OTOG	Body	Opensea
cg18217622	−0.206	8.73E−10	0.00016171	6		IGR	Island
cg18923740	0.090	2.18E−09	0.00032293	1	NBL1	Body	Island
cg12215871	0.115	2.89E−09	0.00035673	7	SDK1	Body	Opensea
cg04802986	0.118	6.75E−09	0.00071486	1	LGR6	Body	Opensea
cg21809624	−0.080	1.40E−08	0.00098142	17		IGR	Opensea
cg08386137	0.097	1.69E−08	0.00104499	6		IGR	Island
cg06279296	0.157	2.03E−08	0.00109495	10	DIP2C	Body	Opensea
cg27603605	0.077	2.61E−08	0.00129099	12	TMEM132B	Body	Opensea
cg15589641	0.112	3.35E−08	0.00145799	1	NBL1	TSS1500	Shore
cg10102108	−0.093	3.73E−08	0.00153659	20		IGR	Opensea
cg04600077	−0.082	5.04E−08	0.00169965	5		IGR	Shore
cg14688342	−0.073	5.53E−08	0.00169965	7	EGFR	Body	Opensea
cg07257824	−0.180	5.62E−08	0.00169965	6		IGR	Island
cg12080079	−0.132	6.27E−08	0.00177299	1	PAX7	Body	Opensea
cg23743013	0.078	7.00E−08	0.00177949	3		IGR	Opensea
cg14579430	0.120	7.09E−08	0.00177949	1	NBL1	5'UTR	Shore
cg01743873	−0.081	8.85E−08	0.0019774	11	CD151	5'UTR	Shore
cg01757548	0.084	9.00E−08	0.0019774	6		IGR	Island

LogFC log₂ Fold Change, Mean Controls Mean of the β-value in control group, Mean GDM Mean of the β-value, Chr Chromosome location, Feature CpG location according with gene regions, Cgi CpG locations according with CpG islands, IGR Inter-genic region

ISSN: 1868-7083