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Table 1 Clinical characteristics of tissue and plasma cohorts

From: Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection

Sample

Tissue

Plasma

Characteristics

polyp

CRC

polyp

CRC

Total (n)

56

62

20

20

Gender

Male

40

45

14

17

Female

16

17

6

3

Age (years)

Median

60.7 (37–94)

60.5 (32–81)

60.5 (50–73)

59.5 (32–74)

 ≥ 50

51

53

20

16

 < 50

5

9

0

4

Stage

I + II

NA

32

NA

8

III + IV

NA

30

NA

12

Lymph node metastasis

No

NA

35

NA

10

Yes

NA

27

NA

10

Microsatellite instability

MSS

NA

58

NA

17

MSI

NA

0

NA

0

NA

NA

4

NA

3

Tumor site

Right-sided

11

9

5

4

Left-sided

22

13

10

4

Rectum

23

40

5

12

Differentiation grade

Highly

NA

1

NA

0

Moderately

NA

56

NA

18

Poorly

NA

5

NA

2

Vascular invasion

No

NA

46

NA

14

Yes

NA

13

NA

3

NA

NA

3

NA

3

Tumor size

 ≥ 5CM

NA

27

NA

6

 < 5CM

NA

35

NA

14

Polyp size

 ≥ 1CM

20

NA

4

NA

 < 1CM

36

NA

16

NA