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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detection

Fig. 3

Validation DNA methylation markers in the tissue validation cohort. A Area under the receiver operating characteristic curves for CpGs identified in the tissue discovery cohort. B Heatmap of 50 differentially methylated CpGs between CRC and polyp tissue. C Scatterplot of methylation level consistency examined by MethylTarget sequencing and EPIC array. D Scatterplot of AUROCs from the 47 CpGs in the tissue discovery set (y-axis) and in the tissue validation set (x-axis)

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