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Fig. 7 | Clinical Epigenetics

Fig. 7

From: DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer

Fig. 7

NRSE region associated with BARHL2 (A) and OTX2 (B). Genomic localization of BARHL2 showing two exons (A) and of OTX2 showing only one exon (B), including the localization of CGI (annotated with the UCSC CGI names) in green box and NRSE in blue box. Regions including altered CpGs are enclosed in red (hypermethylation) and blue (hypomethylation) boxes. The figure shows the β values of tumour and normal samples in PA Replication, CRC and CLL Discovery datasets, and the methylation score values of the cell lines H1 hESC, U87 and HCT116

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