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Fig. 5 | Clinical Epigenetics

Fig. 5

From: DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer

Fig. 5

NRSE region associated with PCDHG cluster. Genomic localization of PCDHG cluster showing only an exon of one gene member, PCDHGC4, including the localization of CGI (annotated with the UCSC CGI names) in green box, NRSE in blue box, CTCF binding sites in light blue boxes and Gene Hancer (promoter/enhancer) in red box. Altered regions are enclosed in red (hypermethylation) and blue (hypomethylation) boxes. The figure shows the β values of tumour and normal samples in PA Discovery and Replication, CRC and CLL Discovery datasets, and the methylation score values of the cell lines H1 hESC, U87 and HCT116

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Clinical Epigenetics

ISSN: 1868-7083

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