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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data

Fig. 3

SOMNiBUS-estimated smooth association parameters associated with methylation differences between SSc disease and controls. Parameters are shown on the logit scale for DMRs annotated to A FLT4, the top ranked autosomal DMG, located on chromosome 5; and B CHST7, the top ranked DMG located on chromosome X. Points (left y-axis) indicate the estimated smoothed coefficient value (vertical axis) at each individual CpG in the region (x-axis), and pointwise confidence intervals are shown in light gray. Structural gene annotations (right y-axis) are shown in shaded boxes: light blue (introns), lilac (exons), green (promoters and first exons; both of which are linked to transcriptional silencing)

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Clinical Epigenetics

ISSN: 1868-7083

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