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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Novel insights into systemic sclerosis using a sensitive computational method to analyze whole-genome bisulfite sequencing data

Fig. 1

SOMNiBUS region-level results. A Manhattan plot SOMNiBUS p-values in CpG regions with ≥ 60 CpGs; the x-axis indicates the starting positions of CpG regions; p-values are plotted on the − log10 scale. Blue and red dashed lines indicate the significance thresholds used in our study (red: Bonferroni corrected threshold of 6.05e−06; blue: 0.05). B Quantile–quantile (QQ) plot of SOMNiBUS region-wide p-values for 8268 CpG regions containing ≥ 60 CpG sites. The confidence interval under the null hypothesis is shown as a gray shaded area. C CpG regions within 1 Mbp density plot, stratified by chromosome

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Clinical Epigenetics

ISSN: 1868-7083

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