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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers

Fig. 2

Principal component analysis (PCA) showing genome-wide DNA methylation similarities between individual tumour, based on 77,113 variably methylated (VM)-CpG probes. Tumour samples of different CRC subgroups are shown in different colours. The MLH1-VUS group includes CRCs from 3 MLH1 germline VUS carriers (two MLH1: c.-11C > T and one MLH1: c.-[28A > G; 7C > T] carriers)

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Clinical Epigenetics

ISSN: 1868-7083

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