Fig. 1
From: Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers
Heatmap of top 20 hypo- and hypermethylated promoters in leukoplakia and OSCC. A Differentially methylated promoters in OPL (grey) when compared to normal (light grey). B Differentially methylated promoters in early-stage OSCC (grey) and advanced-stage OSCC (dark grey) when compared to normal (light grey). The hypo- and hypermethylated promoters are represented in blue and red, respectively. All methylation values were log-transformed and scaled